Many people mix drugs to experience a more intense high or to alleviate the effects of one substance by adding another. Using multiple drugs at the same time is particularly common among high school and college students at parties or other social gatherings.
But combining the prescription opioid hydrocodone with alcohol can produce a range of health effects, from drowsiness to severe liver problems. In some cases, drinking while using the medication can lead to death.
Hydrocodone can be found in popular painkiller brands such as Vicodin, Lortab and Lorcet. Do not drink alcohol while using these medications, and ask your doctor about other substances that may interact with hydrocodone.
Alcohol increases the effects of opioids on the central nervous system, according to the National Institute on Alcohol Abuse and Alcoholism. Consuming painkillers and alcohol together produces sedative effects, causing people to feel extremely tired.
Vicodin, Lortab and Lorcet contain acetaminophen, a substance used to treat minor aches and pains. When mixed with alcohol, acetaminophen breaks down into a toxic product that can lead to liver damage.
Other physical side effects of mixing hydrocodone and alcohol include:
Opioids and alcohol have depressant effects. Sometimes called downers, depressants slow brain activity and reduce anxiety. Combining downers such as hydrocodone and alcohol can inhibit breathing and lower your heart rate, which can be fatal.
Consuming a single Vicodin pill with a small amount of alcohol can result in respiratory depression. A 2017 study published in the journal Anesthesiology found that mixing painkillers and ethanol, the intoxicating ingredient in alcohol, can cause dangerous breathing problems.
Elderly people were most likely to experience respiratory effects after mixing opioids and alcohol, the report found.
According to the National Institute on Drug Abuse, mixing alcohol with prescription opioids, such as hydrocodone, can also result in overdose. An overdose occurs when someone experiences harmful reactions caused by taking too much of a substance.
A 2014 study published in the journal Postgraduate Medicine stated that alcohol can make extended-release opioids release their entire dose at once. This phenomenon, known as “dose dumping,” can increase the risk for overdose.
An untreated overdose can cause death. If your loved one experiences breathing problems after combining hydrocodone and alcohol, call 911 immediately. Emergency workers may be able to prevent an overdose from resulting in long-term health complications.
Hydrocodone and alcohol affect brain function. Each substance releases a neurochemical in the brain called dopamine. But drugs and alcohol can also cause psychological distress. Simultaneously using multiple substances exacerbates these problems.
For example, mixing hydrocodone and alcohol can impair judgment. People who take these substances together have an increased risk for engaging in risky behaviors, such as driving while intoxicated. It is dangerous to operate heavy machinery after consuming alcohol and opioids separately, and it is even more dangerous after consuming them together.
Other physical side effects of mixing hydrocodone and alcohol include:
Researchers in the Postgraduate Medicine study examined the prevalence and consequences of alcohol use among opioid users. They found that many individuals who combined opioids and alcohol felt like they were in a dreamlike trance or not in control of their thoughts.
In 2018, CNN reported a story about an Indiana mother whose two sons died on the same night. The teens had overdosed after mixing hydrocodone and alcohol at high school graduation parties. The mother said her children had never before been in trouble for drinking or using drugs. One bad choice ended their lives.
Your doctor can explain the consequences of mixing painkillers and alcohol. Then you can present this information to your teens so they might be less likely to simultaneously use these substances.
Alcohol is found in many over-the-counter medicines, including cough syrups. Be sure to read the label of any medication you purchase.
To learn more about the effects of mixing hydrocodone and alcohol, you can also call the Substance Abuse and Mental Health Services Administration’s national helpline at 800-662-4357. This 24/7 hotline offers information about prescription opioid abuse and nearby treatment options.
Adolescents experiencing addiction have an increased risk for mixing drugs and alcohol. If your teen is battling hydrocodone addiction, he or she needs treatment. Rehab centers offer evidence-based treatment for various substance abuse problems.
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